Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.77 |
| ▸ | FDPS | P14324 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954267 | 0.95 | ALDH1A1 (0.69) | ALDH1A1FDPSSMN1; SMN2POLBMAPT | |
| SCHEMBL2553586 | 0.90 | ALDH1A1 (0.62) | ALDH1A1FDPSSMN1; SMN2POLBMAPT | |
| SCHEMBL29952641 | 0.87 | ALDH1A1 (1.00) | ALDH1A1FDPSSMN1; SMN2POLBMAPT | |
| SCHEMBL2558222 | 0.87 | ALDH1A1 (0.76) | ALDH1A1FDPSSMN1; SMN2POLBMAPT | |
| SCHEMBL2559441 | 0.85 | HPGD (0.63) | ALDH1A1FDPSSMN1; SMN2MAPTHPGD | |
| SCHEMBL14439518 | 0.84 | FDPS (0.72) | ALDH1A1FDPSSMN1; SMN2POLBMAPT | |
| SCHEMBL15330229 | 0.84 | FDPS (0.63) | ALDH1A1FDPSSMN1; SMN2POLBMAPT | |
| SCHEMBL7466603 | 0.82 | FDPS (0.74) | ALDH1A1FDPSSMN1; SMN2POLBMAPT | |
| SCHEMBL29958425 | 0.82 | ALDH1A1 (0.90) | ALDH1A1FDPSSMN1; SMN2POLBMAPT | |
| SCHEMBL2559517 | 0.82 | ALDH1A1 (0.67) | ALDH1A1FDPSSMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |