Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778338 | 0.78 | ALDH1A1 (0.62) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL29953181 | 0.77 | TSHR (0.55) | ALDH1A1TDP1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL12715334 | 0.77 | TSHR (0.55) | ALDH1A1TDP1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL29954789 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL6370055 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL20328418 | 0.75 | TDP1 (0.66) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL397931 | 0.75 | TDP1 (0.66) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL29650091 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL20328412 | 0.75 | TDP1 (0.66) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL317536 | 0.75 | ALDH1A1 (0.66) | ALDH1A1TDP1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |