Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12715334 | 1.00 | TSHR (0.55) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL12715337 | 0.85 | MAPT (0.51) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL6651702 | 0.81 | TSHR (0.55) | TSHRALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL10036780 | 0.79 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL12625747 | 0.78 | ALDH1A1 (0.56) | TSHRALDH1A1RECQLMAPTMEN1 | |
| SCHEMBL6124791 | 0.78 | MAPT (0.58) | TSHRALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL12405284 | 0.78 | MAPT (0.59) | TSHRALDH1A1CYP3A4HSD17B10MAPT | |
| SCHEMBL12142799 | 0.78 | VCAM1 (0.51) | TSHRALDH1A1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL29952649 | 0.77 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL12619129 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CYP3A4HSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |