Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1418923 | 1.00 | PARP1 (0.51) | PARP1MEN1KMT2ALMNAGAA | |
| SCHEMBL1121664 | 0.88 | MAPT (0.54) | PARP1MEN1KMT2ALMNAGAA | |
| SCHEMBL29958160 | 0.88 | MAPT (0.54) | PARP1MEN1KMT2ALMNAGAA | |
| SCHEMBL4878586 | 0.81 | PARP1 (0.48) | PARP1MEN1KMT2ALMNAMAPT | |
| SCHEMBL31326014 | 0.81 | PARP1 (0.57) | PARP1MEN1KMT2ALMNAGAA | |
| SCHEMBL17678042 | 0.81 | PARP1 (0.57) | PARP1MEN1KMT2ALMNAGAA | |
| SCHEMBL29955688 | 0.77 | MITF (0.51) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL29993384 | 0.76 | PARP1 (0.73) | PARP1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6008297 | 0.76 | PARP1 (0.73) | PARP1MEN1KMT2ALMNAMAPT | |
| SCHEMBL12892057 | 0.74 | CRHBP (0.56) | PARP1MEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |