Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | CRYAB | P02511 | 3/20 | 0.75 |
| ▸ | USP2 | O75604 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | FNTA | P49354 | 1/20 | 0.72 |
| ▸ | FNTB | P49356 | 1/20 | 0.72 |
| ▸ | PTGES | O14684 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | PREP | P48147 | 1/20 | 0.58 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.58 |
| ▸ | CRYAA | P02489 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098744 | 0.89 | MAPT (0.70) | MAPTCRYABUSP2ALDH1A1CYP3A4 | |
| SCHEMBL7166934 | 0.87 | CRYAB (0.70) | MAPTCRYABUSP2ALDH1A1CYP3A4 | |
| SCHEMBL16249832 | 0.86 | MAPT (0.78) | MAPTCRYABUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL14360758 | 0.86 | MAPT (1.00) | MAPTCRYABUSP2ALDH1A1CYP3A4 | |
| SCHEMBL2370125 | 0.86 | MAPT (0.78) | MAPTCRYABUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL2154745 | 0.86 | MAPT (1.00) | MAPTCRYABUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL145835 | 0.86 | MAPT (1.00) | MAPTCRYABUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL1696473 | 0.86 | MAPT (1.00) | MAPTCRYABUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL21348006 | 0.86 | MAPT (1.00) | MAPTCRYABUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL19194030 | 0.86 | MAPT (1.00) | MAPTCRYABUSP2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427773-A1 | METHOD OF DIAGNOSING ASPHYXIA | Keller, Matthias (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128054-A1 | METHOD OF DIAGNOSING ASPHYXIA | BIOCRATES LIFE SCIENCES AG (AT) | 2010-11-11 | — | — | WO | disclosed |
| EP-1451132-A4 | CHEMICAL SYNTHESIS | UNIV WAIKATO (NZ) | 2006-02-08 | — | — | EP | disclosed |
| US-20050038301-A1 | Producing vicinal diols; reacting with hydroxyl group donor and reducing acidic agent | UNIVERSITY OF WAIKATO, THE (NZ) | 2005-02-17 | — | — | US | disclosed |
| EP-1451132-A1 | CHEMICAL SYNTHESIS | THE UNIVERSITY OF WAIKATO (NZ) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003040066-A1 | CHEMICAL SYNTHESIS | THE UNIVERSITY OF WAIKATO (NZ) | 2003-05-15 | — | — | WO | disclosed |