Lanosterol

Lanosterol

SCHEMBL1952146

CC(C)=CCCC(C)C1CCC2(C)C3=C(CCC12C)C1(C)CCC(O)C(C)(C)C1CC3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 1.00
▸ USP2 O75604 2/20 1.00
▸ ALDH1A1 P00352 2/20 1.00
▸ CYP3A4 P08684 2/20 1.00
▸ ALOX15 P16050 2/20 1.00
▸ CRYAB P02511 2/20 1.00
▸ LMNA P02545 1/20 1.00
▸ PTGES O14684 4/20 0.79
▸ FNTA P49354 1/20 0.74
▸ FNTB P49356 1/20 0.74
▸ CRYAA P02489 1/20 0.71
▸ ACHE P22303 1/20 0.62
▸ MEN1 O00255 1/20 0.61
▸ PLA2G1B P04054 1/20 0.61
▸ DNMT1 P26358 1/20 0.61
▸ BLM P54132 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ ATG4B Q9Y4P1 1/20 0.61
▸ HMGCR P04035 1/20 0.61
▸ PREP P48147 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lanosterol SCHEMBL18688634 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL1242765 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL17428540 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL288881 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL11914239 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Euphol SCHEMBL541497 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL20225105 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL15977092 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL21348006 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15
Lanosterol SCHEMBL244737 1.00 MAPT (1.00) MAPTUSP2ALDH1A1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102905763-A Lipids, lipid compositions, and methods of using them NOVARTIS AG 2013-01-30 — — CN claimed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
EP-4522646-A2 APOE LIPOPROTEIN SYSTEMS Kisbee Therapeutics, Inc. (US) 2025-03-19 — — EP disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 — — WO disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
US-20200276211-A1 COMPOUNDS FOR TREATING NEAR VISION DISORDERS VIEWPOINT THERAPEUTICS INC (US) 2020-09-03 — — US disclosed
US-20120289487-A1 Pharmaceutical Use of Multicyclic Compounds as Anti-Aids Agents AMAZÔNIA FITOMEDICAMENTOS LTDA (BR) 2012-11-15 — — US disclosed
CN-102711750-A Pharmaceutical use of polycyclic compounds as anti-AIDS agents AMAZONIA FITOMEDICAMENTOS LTDA 2012-10-03 — — CN disclosed
WO-2011086424-A1 PHARMACEUTICAL USE OF MULTICYCLIC COMPOUNDS MIXTURES AS CONCOMITANT ANTI-CANCER, ANTI-INFLAMMATORY AND ANTI-PAIN AGENTS AMAZONIA FITOMEDICAMENTOS LTDA (BR) 2011-07-21 — — WO disclosed
WO-2011086423-A1 PHARMACEUTICAL USE OF MULTICYCLIC COMPOUNDS AS ANTI-AIDS AGENTS AMAZONIA FITOMEDICAMENTOS LTDA (BR) 2011-07-21 — — WO disclosed
CN-102112133-A Pharmaceutical uses of lanosta-8, 24-dien-3-ols AMAZONIA FITOMEDICAMENTOS LTDA 2011-06-29 — — CN disclosed
US-20110136773-A1 Pharmaceutical Uses of Lanosta-8,24-dien-3-ols AMAZONIA FITOMEDICAMENTOS LTDA (BR) 2011-06-09 — — US disclosed
CN-1863558-B Polyarginine-modified liposomes having nuclear transfer ability JAPAN SCIENCE & TECH AGENCY 2010-12-29 — — CN disclosed
WO-2010015875-A1 PROCESS FOR THE PREPARATION OF LANOSTA-8-ENE COMPOU AMAZONIA FITOMEDICAMENTOS LTDA (BR) 2010-02-11 — — WO disclosed
CN-101522876-A Wheat-germ oil concentrate, a method for the production thereof, a method for producing wheat-germ oil and a medicinal and prophylactic composition based thereon and used for treating sexual dysfuncti OTKRYTOE AKTSIONERNOE OBSCHEST (RU) 2009-09-02 — — CN disclosed
CN-1863558-A Polyarginine-modified liposomes having nuclear transfer ability JAPAN SCIENCE & TECH AGENCY (JP) 2006-11-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200276211-A1 COMPOUNDS FOR TREATING NEAR VISION DISORDERS CRYAB, PDE6C, CRYAA MAPT 510/4885USP2 2084/4885ALDH1A1 1412/4885
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR MAPT 1272/4885USP2 2046/4885ALDH1A1 3260/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885USP2 3358/4885ALDH1A1 3285/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885USP2 3112/4885ALDH1A1 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback