Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.40 |
| ▸ | BBC3 | Q9BXH1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074966 | 0.85 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4ETLR8HRH4 | |
| SCHEMBL29955290 | 0.85 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4ETLR8HRH4 | |
| SCHEMBL18023063 | 0.78 | ALDH1A1 (0.62) | ALDH1A1GAAKDM4ETLR8HRH4 | |
| SCHEMBL28310888 | 0.78 | TLR8 (0.68) | ALDH1A1GAAKDM4ETLR8HRH4 | |
| SCHEMBL18641090 | 0.77 | ALDH1A1 (0.65) | ALDH1A1GAAKDM4ETLR8HRH4 | |
| SCHEMBL9091724 | 0.77 | ALDH1A1 (0.60) | ALDH1A1GAAKDM4ETLR8HRH4 | |
| SCHEMBL28320053 | 0.77 | TLR8 (0.61) | ALDH1A1GAAKDM4ETLR8HRH4 | |
| SCHEMBL18023034 | 0.77 | ALDH1A1 (0.60) | ALDH1A1GAAKDM4ETLR8HRH4 | |
| SCHEMBL18023045 | 0.77 | ALDH1A1 (0.60) | ALDH1A1GAAKDM4ETLR8HRH4 | |
| SCHEMBL31664562 | 0.76 | ALDH1A1 (1.00) | ALDH1A1GAAKDM4ETLR8HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |