Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16008516 | 0.77 | SMN1; SMN2 (0.55) | CYP3A4SMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL891077 | 0.74 | NOTUM (0.68) | NOTUMCYP1A2CYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL28511722 | 0.71 | NOTUM (0.47) | NOTUMCYP1A2CYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL20903079 | 0.70 | NOTUM (0.32) | NOTUMTRIM24TRIM33SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11453426 | 0.69 | NOTUM (0.45) | NOTUMCYP1A2CYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL29952174 | 0.68 | NOTUM (0.44) | NOTUMCYP1A2CYP3A4TRIM24TRIM33 | |
| SCHEMBL5912738 | 0.67 | NOTUM (0.42) | NOTUMCYP1A2CYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL29025896 | 0.65 | CYP1A2 (0.61) | CYP1A2CYP3A4HSD17B10SMN1; SMN2BRD4 | |
| SCHEMBL28647270 | 0.64 | HTT (0.69) | NOTUMSMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL8710048 | 0.64 | ALDH1A1 (0.39) | CYP1A2CYP3A4SMN1; SMN2BRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |