Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23123343 | 0.77 | ALDH1A1 (0.54) | CYP3A4SMN1; SMN2ALDH1A1RAB9AKMT2A | |
| SCHEMBL891077 | 0.74 | NOTUM (0.68) | NOTUMCYP3A4CYP1A2BRPF1SMN1; SMN2 | |
| SCHEMBL14023416 | 0.72 | NOTUM (0.48) | NOTUMCYP3A4CYP1A2BRPF1SMN1; SMN2 | |
| SCHEMBL29951594 | 0.72 | BRPF1 (0.40) | CYP3A4CYP1A2BRPF1SMN1; SMN2HSD17B10 | |
| SCHEMBL2673489 | 0.72 | — | — | |
| SCHEMBL29956998 | 0.69 | NOTUM (0.55) | NOTUMCYP3A4CYP1A2BRPF1SMN1; SMN2 | |
| SCHEMBL29952846 | 0.68 | NOTUM (0.44) | NOTUMCYP3A4CYP1A2BRPF1SMN1; SMN2 | |
| SCHEMBL11307800 | 0.67 | CYP1A2 (0.57) | CYP3A4CYP1A2BRPF1SMN1; SMN2HSD17B10 | |
| SCHEMBL7821237 | 0.66 | PDGFRB (0.53) | NOTUMHSD17B10RAB9A | |
| SCHEMBL9539293 | 0.65 | IGF1R (0.32) | TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |