Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.58 |
| ▸ | ABAT | P80404 | 1/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826371 | 1.00 | ALDH5A1 (0.58) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL28832765 | 0.92 | ALDH1A1 (0.51) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL27680960 | 0.85 | MAPT (0.53) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL335971 | 0.85 | ALDH5A1 (0.62) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL16958437 | 0.83 | TSHR (0.54) | ALDH5A1ABATALDH1A1MAPTTSHR | |
| SCHEMBL5458282 | 0.83 | MAPT (0.51) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL1873374 | 0.82 | ALDH1A1 (0.58) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL31484716 | 0.82 | ALDH5A1 (0.69) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL1466944 | 0.82 | ALDH5A1 (0.69) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL14505293 | 0.79 | TSHR (0.50) | ALDH5A1ABATALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |