Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559134 | 1.00 | KMT2A (0.45) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL2559133 | 1.00 | KMT2A (0.45) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL15332086 | 0.75 | CYP2A6 (0.34) | KMT2AMEN1LMNAALDH1A1HPGD | |
| SCHEMBL15332090 | 0.75 | CYP2A6 (0.34) | KMT2AMEN1LMNAALDH1A1HPGD | |
| SCHEMBL11208205 | 0.75 | HDAC4 (0.37) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL8450486 | 0.74 | NPC1 (0.64) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL26704623 | 0.74 | MEN1 (0.52) | KMT2AMEN1LMNAALDH1A1HPGD | |
| SCHEMBL28010180 | 0.74 | MEN1 (0.52) | KMT2AMEN1LMNAALDH1A1HPGD | |
| SCHEMBL15331249 | 0.73 | ALDH1A1 (0.38) | KMT2AMEN1TDP1ALDH1A1HPGD | |
| SCHEMBL15331247 | 0.73 | ALDH1A1 (0.38) | KMT2AMEN1TDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |