Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24373532 | 0.78 | CYP3A4 (0.60) | ERN1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL31648883 | 0.78 | ERN1 (0.44) | ERN1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL9718010 | 0.77 | RAPGEF4 (0.39) | ERN1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL14877416 | 0.76 | ERN1 (0.56) | ERN1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL1312151 | 0.76 | ERN1 (0.56) | ERN1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL686293 | 0.74 | ERN1 (0.54) | ERN1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL234943 | 0.74 | CYP3A4 (0.58) | CYP3A4RAPGEF4TSHRCHRM1ALOX15 | |
| SCHEMBL10325195 | 0.73 | ERN1 (0.52) | ERN1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL14901949 | 0.73 | ERN1 (0.52) | ERN1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL13217149 | 0.73 | ERN1 (0.52) | ERN1ALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |