Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 11/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30322297 | 0.77 | ALDH1A1 (0.36) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL29952878 | 0.77 | ERN1 (0.52) | RAPGEF4KMT2ALMNACYP3A4CHRM1 | |
| SCHEMBL1611521 | 0.76 | ESR1 (0.35) | RAPGEF4KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL18849429 | 0.74 | RAPGEF4 (0.33) | RAPGEF4KMT2ASMN1; SMN2ERN1TP53 | |
| SCHEMBL234943 | 0.74 | CYP3A4 (0.58) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL10289692 | 0.73 | RAPGEF4 (0.35) | RAPGEF4ERN1TP53TDP1 | |
| SCHEMBL22579527 | 0.73 | ALDH1A1 (0.38) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL9717980 | 0.73 | CYP3A4 (0.36) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL28510556 | 0.73 | ALDH1A1 (0.33) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL8259227 | 0.73 | ALDH1A1 (0.46) | KMT2ALMNACYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348906-B1 | HEAT-RESISTANT RESIN COMPOSITION | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1992-10-07 | — | — | EP | disclosed |
| US-4994515-A | Resin of styrene and unsaturated imide, high impact thermoplastic, bromine-containing reaction product, silicon resin or compound | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0348906-A1 | Heat-resistant resin composition | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-01-03 | — | — | EP | disclosed |