Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22683815 | 1.00 | APP (0.45) | APPMGLLABL1KCNH2TMEM97 | |
| SCHEMBL29953648 | 0.85 | MGLL (0.39) | APPMGLLABL1ENPP2CA1 | |
| SCHEMBL1496432 | 0.81 | MGLL (0.39) | MGLLABL1ENPP2CA1CA2 | |
| SCHEMBL31437950 | 0.81 | MGLL (0.39) | MGLLABL1ENPP2CA1CA2 | |
| SCHEMBL29953617 | 0.80 | MGLL (0.38) | MGLLABL1ENPP2CA1CA2 | |
| SCHEMBL29955486 | 0.80 | TTR (0.42) | MGLLABL1ENPP2CA1CA2 | |
| SCHEMBL2409490 | 0.80 | TTR (0.42) | MGLLABL1ENPP2CA1CA2 | |
| SCHEMBL20638904 | 0.79 | ENPP2 (0.41) | MGLLABL1ENPP2CA1CA2 | |
| SCHEMBL29953216 | 0.79 | ENPP2 (0.41) | MGLLABL1ENPP2CA1CA2 | |
| SCHEMBL491621 | 0.78 | EPHX2 (0.50) | MGLLABL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |