Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL870480 | 1.00 | KDM4A (0.42) | KDM4AGRM2RPS6KA1GPR119CTSS | |
| SCHEMBL29957341 | 0.89 | KDM4A (0.42) | KDM4AGRM2RPS6KA1GPR119CTSS | |
| SCHEMBL13167894 | 0.84 | IDO1 (0.47) | KDM4AKCNA5DRD2DDR1SMN1; SMN2 | |
| SCHEMBL23735207 | 0.83 | EGFR (0.44) | KDM4AGRM2RPS6KA1GPR119CTSS | |
| SCHEMBL3593392 | 0.83 | GFER (0.45) | KDM4ABRD4L3MBTL1 | |
| SCHEMBL27669311 | 0.82 | GRM2 (0.47) | KDM4AGRM2RPS6KA1GPR119CTSS | |
| SCHEMBL23105713 | 0.82 | KDM4A (0.43) | KDM4AGRM2RPS6KA1GPR119CTSS | |
| SCHEMBL2443309 | 0.82 | GRM2 (0.44) | KDM4AGRM2RPS6KA1GPR119CTSS | |
| SCHEMBL29555276 | 0.82 | KDM4A (0.43) | KDM4AGRM2RPS6KA1GPR119CTSS | |
| SCHEMBL1654680 | 0.82 | KDM4A (0.45) | KDM4AGRM2RPS6KA1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |