Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951546 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL14645352 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL28370258 | 0.79 | POLB (0.43) | SMN1; SMN2ALDH1A1ABL1KDM4EPOLB | |
| SCHEMBL3950221 | 0.79 | CSNK2A1 (0.52) | ALDH1A1KDM4EPOLBMEN1CYP2D6 | |
| SCHEMBL5127944 | 0.76 | RXRB (0.49) | ALDH1A1KDM4EPOLBAKR1C3AKR1C2 | |
| SCHEMBL3800923 | 0.75 | KIF11 (0.38) | ABL1MEN1CYP2D6MAPTKMT2A | |
| SCHEMBL2592316 | 0.75 | RARB (0.45) | ALDH1A1KDM4E | |
| SCHEMBL2801319 | 0.74 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1ABL1KDM4EPOLB | |
| SCHEMBL3788717 | 0.74 | KIF11 (0.37) | SMN1; SMN2ALDH1A1ABL1KDM4EMEN1 | |
| SCHEMBL2588369 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |