SCHEMBL29952917

SCHEMBL29952917

COc1ccc(B(O)O)cc1S(=O)(=O)N1CCOCC1

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
POLB P06746 1/20 0.58
KMT2A Q03164 2/20 0.57
NPC1 O15118 1/20 0.56
TSHR P16473 1/20 0.55
BRD4 O60885 1/20 0.55
BRD2 P25440 1/20 0.55
BRD3 Q15059 1/20 0.55
LMNA P02545 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3707131 1.00 ALDH1A1 (0.59) ALDH1A1NPSR1POLBKMT2ANPC1
SCHEMBL17393891 0.88 ALDH1A1 (0.64) ALDH1A1POLBKMT2ATSHRLMNA
SCHEMBL29952555 0.88 ALDH1A1 (0.64) ALDH1A1POLBKMT2ATSHRLMNA
SCHEMBL29951820 0.87 TSHR (0.67) ALDH1A1POLBKMT2ATSHRLMNA
SCHEMBL16599324 0.82 POLB (0.62) ALDH1A1NPSR1POLBKMT2ANPC1
SCHEMBL15120570 0.81 KMT2A (0.81) ALDH1A1NPSR1POLBKMT2ANPC1
SCHEMBL23847020 0.80 ALDH1A1 (0.63) ALDH1A1NPSR1POLBKMT2ANPC1
SCHEMBL30511773 0.80 ALDH1A1 (0.63) ALDH1A1NPSR1POLBKMT2ANPC1
SCHEMBL30511774 0.80 ALDH1A1 (0.63) ALDH1A1NPSR1POLBKMT2ANPC1
SCHEMBL15052436 0.80 GAA (0.77) ALDH1A1NPSR1POLBKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed