Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17393891 | 0.99 | ALDH1A1 (0.64) | TSHRKDM4EALDH1A1GAAPOLB | |
| SCHEMBL29952555 | 0.99 | ALDH1A1 (0.64) | TSHRKDM4EALDH1A1GAAPOLB | |
| SCHEMBL3707131 | 0.87 | ALDH1A1 (0.59) | TSHRALDH1A1POLBKMT2ALMNA | |
| SCHEMBL29952917 | 0.87 | ALDH1A1 (0.59) | TSHRALDH1A1POLBKMT2ALMNA | |
| SCHEMBL29944324 | 0.80 | KMT2A (0.74) | TSHRKDM4EALDH1A1GAAPOLB | |
| SCHEMBL29575490 | 0.79 | GAA (0.97) | TSHRKDM4EALDH1A1GAAPOLB | |
| SCHEMBL1001171 | 0.78 | RAB9A (0.72) | TSHRKDM4EALDH1A1GAAPOLB | |
| SCHEMBL7661191 | 0.78 | RAB9A (0.72) | TSHRKDM4EALDH1A1GAAPOLB | |
| SCHEMBL7661631 | 0.77 | RAB9A (0.73) | TSHRKDM4EALDH1A1GAAPOLB | |
| SCHEMBL9633286 | 0.75 | TSHR (0.62) | TSHRKDM4EALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |