Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956888 | 0.85 | HTT (0.71) | HTTGAAUSP2KMT2AMEN1 | |
| SCHEMBL15330891 | 0.82 | ALDH1A1 (0.63) | HTTGAAKMT2AMEN1NPSR1 | |
| SCHEMBL2559638 | 0.81 | ALDH1A1 (0.53) | HPGDUSP2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2562910 | 0.81 | ALDH1A1 (0.54) | HTTHPGDGAAUSP2KMT2A | |
| SCHEMBL6192050 | 0.79 | KMT2A (0.78) | HTTGAAUSP2KMT2AMEN1 | |
| SCHEMBL27711029 | 0.78 | HPGD (0.43) | HTTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL30996750 | 0.77 | CYP2D6 (0.60) | HPGDALDH1A1 | |
| SCHEMBL1536071 | 0.77 | CYP2D6 (0.60) | HPGDALDH1A1 | |
| SCHEMBL3844592 | 0.77 | HTT (0.79) | HTTGAAUSP2KMT2AMEN1 | |
| SCHEMBL29957137 | 0.77 | KDM4E (0.42) | HPGDKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |