Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953165 | 0.81 | CYP2A6 (0.41) | KMT2ATRIM24TRIM33ALDH1A1KDM4E | |
| SCHEMBL29952237 | 0.77 | ERN1 (0.40) | KMT2ATRIM24TRIM33ALDH1A1KDM4E | |
| SCHEMBL31748624 | 0.74 | CYP2A6 (0.41) | KMT2ATRIM24TRIM33ALDH1A1KDM4E | |
| SCHEMBL1714533 | 0.71 | KMT2A (0.53) | KMT2ATRIM24TRIM33ALDH1A1KDM4E | |
| SCHEMBL29953043 | 0.71 | KMT2A (0.53) | KMT2ATRIM24TRIM33ALDH1A1KDM4E | |
| SCHEMBL13132293 | 0.71 | KMT2A (0.53) | KMT2ATRIM24TRIM33ALDH1A1KDM4E | |
| SCHEMBL29952450 | 0.71 | KMT2A (0.53) | KMT2ATRIM24TRIM33ALDH1A1KDM4E | |
| SCHEMBL23725349 | 0.70 | KMT2A (0.47) | KMT2ATRIM24TRIM33ALDH1A1KDM4E | |
| SCHEMBL29953688 | 0.70 | KMT2A (0.51) | KMT2AALDH1A1KDM4EMAPTCCNT1 | |
| SCHEMBL1713542 | 0.70 | KMT2A (0.51) | KMT2AALDH1A1KDM4EMAPTCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |