Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952970 | 0.77 | KMT2A (0.41) | ALDH1A1MAPTKDM4ECYP3A4KMT2A | |
| SCHEMBL29953165 | 0.77 | CYP2A6 (0.41) | ALDH1A1MAPTKDM4EPRKDCKMT2A | |
| SCHEMBL29953854 | 0.72 | KMT2A (0.46) | ERN1ALDH1A1MAPTCYP3A4KMT2A | |
| SCHEMBL4355680 | 0.72 | KMT2A (0.46) | ERN1ALDH1A1MAPTCYP3A4KMT2A | |
| SCHEMBL27831883 | 0.69 | TSHR (0.47) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL19204027 | 0.69 | MEN1 (0.41) | ALDH1A1KDM4ECYP3A4HSD17B10KMT2A | |
| SCHEMBL7661967 | 0.69 | TRIM24 (0.50) | ERN1ALDH1A1MAPTKDM4ETRIM24 | |
| SCHEMBL13132293 | 0.68 | KMT2A (0.53) | ALDH1A1MAPTKDM4EKMT2ATRIM24 | |
| SCHEMBL29953043 | 0.68 | KMT2A (0.53) | ALDH1A1MAPTKDM4EKMT2ATRIM24 | |
| SCHEMBL31748624 | 0.68 | CYP2A6 (0.41) | ERN1ALDH1A1MAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |