Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22960490 | 0.88 | TSHR (0.46) | TSHRKDM4EL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL257887 | 0.82 | MRGPRX4 (0.49) | TSHRKDM4EL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL29952567 | 0.78 | GAA (0.34) | KDM4EALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL178228 | 0.78 | TSHR (0.62) | TSHRKDM4EPOLBENPP2LIPE | |
| SCHEMBL18500353 | 0.77 | ERN1 (0.41) | TSHRKDM4EENPP2LIPEMRGPRX4 | |
| SCHEMBL29954345 | 0.77 | LIPE (0.53) | NPC1ENPP2LIPEMRGPRX4 | |
| SCHEMBL212034 | 0.77 | LIPE (0.53) | NPC1ENPP2LIPEMRGPRX4 | |
| SCHEMBL30963264 | 0.76 | TSHR (0.50) | TSHRKDM4EL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL29956910 | 0.76 | ALDH1A1 (0.41) | KDM4ENPC1ALDH1A1POLBMAPT | |
| SCHEMBL29952361 | 0.76 | LIPE (0.47) | TSHRKDM4EL3MBTL1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |