Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561752 | 0.89 | KMT2A (0.49) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15330964 | 0.85 | ALDH1A1 (0.56) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29953338 | 0.83 | KDM4E (0.67) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2554750 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL692841 | 0.82 | MAPT (0.67) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2560314 | 0.82 | SMN1; SMN2 (0.71) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29951938 | 0.81 | PTGDR2 (0.60) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15331042 | 0.81 | NPSR1 (0.54) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2559381 | 0.80 | MEN1 (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2562688 | 0.80 | GAA (0.47) | POLBALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |