Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951784 | 0.90 | POLB (0.60) | KDM4ERAB9APOLBALDH1A1MAPT | |
| SCHEMBL2554953 | 0.85 | KDM4E (0.71) | KDM4ERAB9APOLBALDH1A1MAPT | |
| SCHEMBL29953028 | 0.83 | POLB (0.58) | KDM4ERAB9APOLBALDH1A1MAPT | |
| SCHEMBL29952430 | 0.83 | RAB9A (0.72) | KDM4ERAB9AALDH1A1MAPTNPC1 | |
| SCHEMBL8121860 | 0.82 | KDM4E (0.67) | KDM4ERAB9AALDH1A1MAPTNPC1 | |
| SCHEMBL2557701 | 0.82 | KDM4E (0.78) | KDM4ERAB9AALDH1A1MAPTNPC1 | |
| SCHEMBL2561823 | 0.82 | RAB9A (0.67) | KDM4ERAB9APOLBALDH1A1MAPT | |
| SCHEMBL2554836 | 0.81 | KDM4E (0.69) | KDM4ERAB9AALDH1A1MAPTCYP2D6 | |
| SCHEMBL5882010 | 0.81 | KDM4E (0.64) | KDM4ERAB9APOLBALDH1A1MAPT | |
| SCHEMBL15331584 | 0.80 | RAB9A (0.64) | KDM4ERAB9AALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |