Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.36 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248676 | 0.86 | TTR (0.44) | SMN1; SMN2ALDH1A1TTRKMT2AKDM4E | |
| SCHEMBL29956390 | 0.82 | POLB (0.54) | ALDH1A1TTRKMT2AKDM4EMAPT | |
| SCHEMBL29950679 | 0.82 | HSD17B10 (0.47) | ALDH1A1KMT2ALMNAMAPTPSMB8 | |
| SCHEMBL29952586 | 0.82 | PSMB5 (0.44) | SMN1; SMN2ALDH1A1PSMB8PSMB5HPGD | |
| SCHEMBL18282327 | 0.82 | HSD17B10 (0.47) | ALDH1A1KMT2ALMNAMAPTPSMB8 | |
| SCHEMBL29953833 | 0.80 | HSD17B10 (0.62) | ALDH1A1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL660617 | 0.79 | MEN1 (0.50) | SMN1; SMN2ALDH1A1TTRKMT2AKDM4E | |
| SCHEMBL29712893 | 0.79 | MEN1 (0.50) | SMN1; SMN2ALDH1A1TTRKMT2AKDM4E | |
| SCHEMBL29919280 | 0.79 | GAA (0.53) | ALDH1A1PSMB8PSMB5GAAPSMB11 | |
| SCHEMBL3326392 | 0.79 | GAA (0.53) | ALDH1A1PSMB8PSMB5GAAPSMB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |