Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.42 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.42 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282327 | 1.00 | HSD17B10 (0.47) | HSD17B10KMT2ALMNAHPGDCYP1A2 | |
| SCHEMBL29953833 | 0.88 | HSD17B10 (0.62) | HSD17B10KMT2AHPGDCYP1A2CYP3A4 | |
| SCHEMBL29955017 | 0.88 | POLB (0.51) | LMNAHPGDCYP1A2CYP2C19NPC1 | |
| SCHEMBL29952526 | 0.85 | HPGD (0.61) | HSD17B10KMT2ALMNAHPGDCYP1A2 | |
| SCHEMBL29953067 | 0.82 | SMN1; SMN2 (0.51) | HSD17B10KMT2ALMNAHPGDCYP1A2 | |
| SCHEMBL29954131 | 0.81 | LMNA (0.42) | KMT2ALMNATSHRHTTPSMB8 | |
| SCHEMBL7218397 | 0.80 | LMNA (0.67) | HSD17B10KMT2ALMNAHPGDCYP1A2 | |
| SCHEMBL18789436 | 0.80 | MEN1 (0.54) | KMT2AHPGDNPC1ALDH1A1 | |
| SCHEMBL470072 | 0.79 | SMN1; SMN2 (0.43) | KMT2ALMNAHPGDNPC1HTT | |
| SCHEMBL12163930 | 0.79 | LMNA (0.53) | HSD17B10KMT2ALMNAHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |