Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.42 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.42 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.42 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.42 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.42 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.42 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.42 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.42 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047592 | 0.88 | ALDH1A1 (0.50) | PSMB5HPGDALOX5ALDH1A1GAA | |
| SCHEMBL29956917 | 0.88 | ALDH1A1 (0.50) | PSMB5HPGDALOX5ALDH1A1GAA | |
| SCHEMBL29953067 | 0.82 | SMN1; SMN2 (0.51) | PSMB5HPGDPSMB8PSMB11PSMA7 | |
| SCHEMBL4063989 | 0.81 | ALOX5 (0.42) | PSMB5PSMB8PSMB11PSMA7PSMB1 | |
| SCHEMBL29952959 | 0.81 | ALOX5 (0.42) | PSMB5PSMB8PSMB11PSMA7PSMB1 | |
| SCHEMBL27409724 | 0.80 | ALDH1A1 (0.61) | PSMB5HPGDPSMB8PSMB11PSMA7 | |
| SCHEMBL660617 | 0.79 | MEN1 (0.50) | HPGDALDH1A1GAATSHRHTT | |
| SCHEMBL29712893 | 0.79 | MEN1 (0.50) | HPGDALDH1A1GAATSHRHTT | |
| SCHEMBL13886794 | 0.79 | ITGB1 (0.47) | HPGDALOX5ALDH1A1GAAKCNA3 | |
| SCHEMBL29956390 | 0.78 | POLB (0.54) | PSMB5PSMB8ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |