Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951773 | 0.95 | KCNK3 (0.44) | HTTNR1I2KCNK3LMNAHSD11B1 | |
| SCHEMBL5220234 | 0.82 | HTT (0.46) | HTTNR1I2KCNK3LMNAHSD11B1 | |
| SCHEMBL3276717 | 0.82 | HTT (0.59) | HTTNR1I2KCNK3LMNAHSD11B1 | |
| SCHEMBL18878615 | 0.82 | KCNK3 (0.55) | HTTNR1I2KCNK3LMNAHSD11B1 | |
| SCHEMBL3276714 | 0.82 | HTT (0.46) | HTTNR1I2KCNK3LMNAHSD11B1 | |
| SCHEMBL5220242 | 0.82 | HTT (0.59) | HTTNR1I2KCNK3LMNAHSD11B1 | |
| SCHEMBL31153756 | 0.81 | HTT (0.45) | HTTNR1I2KCNK3LMNAHSD11B1 | |
| SCHEMBL262183 | 0.80 | SLC6A1 (0.45) | LMNASLC6A1RAB9A | |
| SCHEMBL16511108 | 0.79 | NR1I2 (0.61) | HTTNR1I2KCNK3LMNAHSD11B1 | |
| SCHEMBL2563296 | 0.79 | POLB (0.38) | HTTNR1I2LMNAHSD11B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |