Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953085 | 0.95 | HTT (0.43) | KCNK3LMNACYP3A4CYP2D6KCNH2 | |
| SCHEMBL2562312 | 0.80 | SLC6A1 (0.38) | KCNK3LMNACYP3A4CYP2D6KCNH2 | |
| SCHEMBL22808905 | 0.79 | ALDH1A1 (0.46) | KCNK3LMNACYP3A4CYP2D6KCNH2 | |
| SCHEMBL18878615 | 0.78 | KCNK3 (0.55) | KCNK3LMNACYP3A4CYP2D6KCNH2 | |
| SCHEMBL5220234 | 0.78 | HTT (0.46) | KCNK3LMNACYP3A4CYP2D6KCNH2 | |
| SCHEMBL3276717 | 0.78 | HTT (0.59) | KCNK3LMNACYP3A4CYP2D6KCNH2 | |
| SCHEMBL18801590 | 0.78 | ALDH1A1 (0.45) | KCNK3LMNACYP3A4CYP2D6KCNH2 | |
| SCHEMBL19478747 | 0.78 | KCNK3 (0.42) | KCNK3LMNACYP3A4CYP2D6KCNH2 | |
| SCHEMBL5220242 | 0.78 | HTT (0.59) | KCNK3LMNACYP3A4CYP2D6KCNH2 | |
| SCHEMBL3276714 | 0.78 | HTT (0.46) | KCNK3LMNACYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |