Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MMP14 | P50281 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4290135 | 0.80 | LMNA (0.32) | LMNASMN1; SMN2CYP3A4MAPTRXFP1 | |
| SCHEMBL29446706 | 0.80 | LMNA (0.32) | LMNASMN1; SMN2CYP3A4MAPTRXFP1 | |
| SCHEMBL19549878 | 0.78 | FFAR1 (0.34) | LMNASMN1; SMN2RXFP1ENPP2 | |
| SCHEMBL29956403 | 0.78 | FFAR1 (0.34) | LMNASMN1; SMN2RXFP1ENPP2 | |
| SCHEMBL29766613 | 0.77 | NPC1 (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL12327210 | 0.77 | NPC1 (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL29953634 | 0.76 | CCR1 (0.34) | LMNAKDM4EMEN1ALDH1A1KMT2A | |
| Water SCHEMBL29955324 | 0.75 | NPC1 (0.31) | — | |
| SCHEMBL316298 | 0.75 | — | — | |
| SCHEMBL29951106 | 0.74 | ENPP2 (0.30) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |