Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020085 | 1.00 | LMNA (0.48) | LMNACYP2C9SLC6A2SLC6A3MAPK1 | |
| SCHEMBL4667124 | 0.75 | CYP2C9 (0.48) | LMNACYP2C9SLC6A2SLC6A3CYP1A2 | |
| SCHEMBL3438658 | 0.74 | — | — | |
| SCHEMBL9387173 | 0.70 | LMNA (0.55) | LMNACYP2C9SLC6A2SLC6A3MAPK1 | |
| SCHEMBL4722010 | 0.70 | CYP2C9 (0.55) | LMNACYP2C9SLC6A2SLC6A3CYP1A2 | |
| SCHEMBL2131516 | 0.70 | LMNA (0.55) | LMNACYP2C9SLC6A2SLC6A3MAPK1 | |
| SCHEMBL2131520 | 0.70 | LMNA (0.55) | LMNACYP2C9SLC6A2SLC6A3MAPK1 | |
| SCHEMBL2442821 | 0.70 | LMNA (0.55) | LMNACYP2C9SLC6A2SLC6A3MAPK1 | |
| SCHEMBL24473924 | 0.70 | LMNA (0.38) | LMNACYP2C9TDP1 | |
| SCHEMBL15372499 | 0.70 | LMNA (0.38) | LMNACYP2C9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |