SCHEMBL29953219

SCHEMBL29953219

OB(O)c1ccccc1-c1cccnc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.52
CYP3A4 P08684 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP1A2 P05177 1/20 0.52
PTGS2 P35354 1/20 0.50
CYP11B1 P15538 3/20 0.47
CYP2E1 P05181 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2B6 P20813 1/20 0.47
CYP2C19 P33261 1/20 0.47
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
MAPT P10636 1/20 0.45
ALOX15 P16050 1/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560340 1.00 CYP2A6 (0.52) CYP2A6CYP3A4ALDH1A1CYP1A2PTGS2
SCHEMBL28301564 0.87 PTGS2 (0.43) CYP2A6CYP3A4ALDH1A1CYP1A2PTGS2
SCHEMBL2650696 0.82 CYP11B1 (0.47) CYP2A6CYP3A4ALDH1A1CYP1A2PTGS2
SCHEMBL20541087 0.81 CYP2A6 (0.70) CYP2A6CYP3A4ALDH1A1CYP1A2PTGS2
SCHEMBL30026143 0.81 CYP2A6 (0.70) CYP2A6CYP3A4ALDH1A1CYP1A2PTGS2
SCHEMBL28019540 0.80 CYP11B1 (0.51) CYP2A6CYP3A4ALDH1A1CYP1A2PTGS2
SCHEMBL23152013 0.80 NOTUM (0.44) ALDH1A1SMN1; SMN2LMNATP53MAPT
SCHEMBL28019022 0.80 CYP11B1 (0.50) CYP2A6CYP3A4ALDH1A1CYP1A2PTGS2
SCHEMBL21110859 0.79 CYP2A6 (0.67) CYP2A6CYP3A4ALDH1A1CYP1A2PTGS2
SCHEMBL21933 0.79 ALDH1A1 (0.48) CYP2A6ALDH1A1PTGS2HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111183134-B Heterocyclic compound and organic light-emitting device comprising the same LT素材株式会社 2025-05-09 CN disclosed
CN-116425730-A Organic electroluminescent compounds and use thereof 宁波卢米蓝新材料有限公司 2023-07-14 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed