Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955647 | 0.88 | PPARA (0.43) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL29951963 | 0.80 | CYP1A2 (0.59) | NPC1RAB9ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL9071102 | 0.80 | TDP1 (0.59) | NPC1RAB9ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL558343 | 0.77 | RAB9A (0.68) | NPC1RAB9ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL10220120 | 0.75 | ACACB (0.44) | NPC1RAB9ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL12963734 | 0.73 | NPC1 (0.53) | NPC1RAB9ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL10223635 | 0.73 | NPC1 (0.44) | NPC1RAB9ACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL29951157 | 0.73 | HTT (0.58) | CYP1A2CYP3A4GAACYP2C9DYRK1A | |
| SCHEMBL29395035 | 0.69 | MGLL (0.43) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL27197247 | 0.69 | MGLL (0.43) | NPC1RAB9ASMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |