Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951023 | 0.77 | PGK1 (0.38) | ALDH1A1 | |
| SCHEMBL10211677 | 0.76 | CYP2D6 (0.39) | GAAPOLBALDH1A1TDP1MAPT | |
| SCHEMBL5252725 | 0.74 | TAAR1 (0.60) | TAAR1GAAPOLBALDH1A1TDP1 | |
| SCHEMBL9491792 | 0.74 | TAAR1 (0.74) | TAAR1GAAPOLBALDH1A1TDP1 | |
| SCHEMBL29957198 | 0.73 | TAAR1 (0.46) | TAAR1ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL376960 | 0.73 | TAAR1 (0.46) | TAAR1ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL5357592 | 0.72 | TAAR1 (0.58) | TAAR1GAAPOLBALDH1A1TDP1 | |
| SCHEMBL2090774 | 0.72 | TAAR1 (0.58) | TAAR1GAAPOLBALDH1A1TDP1 | |
| SCHEMBL29462885 | 0.72 | TAAR1 (0.58) | TAAR1GAAPOLBALDH1A1TDP1 | |
| SCHEMBL269825 | 0.72 | TAAR1 (0.58) | TAAR1GAAPOLBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |