SCHEMBL29951023

SCHEMBL29951023

[C-]#[N+]Cc1cc(C[N+]#[C-])c(C)cc1C

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953337 0.77 TAAR1 (0.50) ALDH1A1
SCHEMBL10211677 0.71 CYP2D6 (0.39) ALDH1A1
SCHEMBL29957198 0.70 TAAR1 (0.46) ALDH1A1
SCHEMBL3893595 0.67 GPR3 (0.40)
SCHEMBL29957524 0.67 ESR1 (0.41) ALDH1A1
SCHEMBL29952702 0.67 HRH3 (0.36) ALDH1A1
SCHEMBL20231823 0.65 PGK1 (0.50) PGK1PGK2ALDH1A1
SCHEMBL8133418 0.65 PGK1 (0.39) PGK1PGK2ALDH1A1
SCHEMBL12629117 0.63 PGK1 (0.38) PGK1PGK2
SCHEMBL29954468 0.63 IDH1 (0.35) PGK1PGK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed