Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330847 | 0.87 | KDM4E (0.52) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL15331225 | 0.86 | CYP2A13 (0.51) | KDM4ESMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL2554986 | 0.85 | KDM4E (0.45) | KDM4ESMN1; SMN2ALDH1A1HRH3GFER | |
| SCHEMBL428266 | 0.85 | CYP2A13 (0.56) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL29044212 | 0.84 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1CXCR3BCHE | |
| SCHEMBL30519205 | 0.84 | KDM4E (0.44) | KDM4ESMN1; SMN2ALDH1A1CXCR3BCHE | |
| SCHEMBL2562320 | 0.82 | KDM4E (0.47) | KDM4ESMN1; SMN2ALDH1A1HTTHRH3 | |
| SCHEMBL19211657 | 0.81 | KDM4E (0.42) | KDM4ESMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL2563675 | 0.80 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2ALDH1A1HTTHRH3 | |
| SCHEMBL29952220 | 0.79 | ADRB2 (0.46) | KDM4ESMN1; SMN2ALDH1A1HTTCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |