Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956306 | 0.83 | THRA (0.44) | RIPK1ALOX5HSD11B1KDM4EHTT | |
| SCHEMBL28948440 | 0.82 | KDM4E (0.51) | RIPK1ALOX5HSD11B1KDM4EHTT | |
| SCHEMBL29958592 | 0.79 | KDM4E (0.49) | RIPK1ALOX5HSD11B1KDM4EHTT | |
| SCHEMBL1246921 | 0.78 | RIPK1 (0.47) | RIPK1ALOX5HSD11B1KDM4EHTT | |
| SCHEMBL7169443 | 0.77 | RIPK1 (0.46) | RIPK1ALOX5HSD11B1KDM4EHTT | |
| SCHEMBL10241255 | 0.77 | RIPK1 (0.50) | RIPK1ALOX5HSD11B1KDM4EHTT | |
| SCHEMBL5931188 | 0.75 | — | — | |
| SCHEMBL733240 | 0.74 | — | — | |
| SCHEMBL12155805 | 0.74 | THRA (0.51) | RIPK1ALOX5HSD11B1KDM4EHTT | |
| SCHEMBL16523570 | 0.73 | TSHR (0.51) | KDM4EHTTL3MBTL1GFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |