SCHEMBL29953364

SCHEMBL29953364

O=Cc1cc(O)cc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.55
ERN1 O75460 6/20 0.51
ESR1 P03372 2/20 0.51
ESR2 Q92731 2/20 0.51
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
MAPT P10636 1/20 0.48
MPI P34949 1/20 0.48
CDC25B P30305 3/20 0.45
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
TRPM4 Q8TD43 1/20 0.42
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3268303 1.00 NQO2 (0.55) NQO2ERN1ESR1ESR2MEN1
SCHEMBL30074753 0.82 ERN1 (0.47) NQO2ERN1ESR1ESR2MEN1
Formamide SCHEMBL9732527 0.80 NQO2 (0.47) NQO2ERN1ESR1ESR2MEN1
SCHEMBL1506780 0.80 NQO2 (0.55) NQO2ERN1ESR1ESR2MEN1
SCHEMBL29956684 0.78 ERN1 (0.44) NQO2ERN1ESR1ESR2MEN1
SCHEMBL3067367 0.78 ERN1 (0.44) NQO2ERN1ESR1ESR2MEN1
SCHEMBL9732522 0.78 EGFR (0.55) NQO2ERN1ESR1ESR2MEN1
SCHEMBL3676494 0.78 ERN1 (0.45) ERN1ESR1ESR2MEN1KMT2A
SCHEMBL31141573 0.78 ERN1 (0.45) ERN1MEN1KMT2AKDM4EALDH1A1
SCHEMBL29953557 0.78 ERN1 (0.45) ERN1ESR1ESR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118731194-A Detection method of alkyl diamine 四川科伦药物研究院有限公司 2024-10-01 CN claimed
CN-118731194-A Detection method of alkyl diamine 四川科伦药物研究院有限公司 2024-10-01 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed