SCHEMBL3067367

SCHEMBL3067367

O=Cc1cccc2cc(O)ccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 3/20 0.44
CYP1A2 P05177 1/20 0.43
ESR1 P03372 7/20 0.43
ESR2 Q92731 7/20 0.43
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
TLR8 Q9NR97 1/20 0.41
CLK1 P49759 1/20 0.41
DYRK1A Q13627 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
NQO2 P16083 1/20 0.39
THRB P10828 2/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
THRA P10827 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29956684 1.00 ERN1 (0.44) ERN1CYP1A2ESR1ESR2TRIM24
SCHEMBL9669003 0.85 MCL1 (0.49) ERN1CYP1A2ESR1ESR2TRIM24
SCHEMBL9097166 0.84 ESR1 (0.48) ERN1CYP1A2ESR1ESR2TRIM24
SCHEMBL30365636 0.81 CYP1A2 (0.43) CYP1A2ESR1ESR2HSD17B1HSD17B2
SCHEMBL1506789 0.81 CYP1A2 (0.43) CYP1A2ESR1ESR2HSD17B1HSD17B2
SCHEMBL28189143 0.81 CYP1A2 (0.46) ERN1CYP1A2ESR1ESR2CLK1
SCHEMBL19066454 0.80 ESR1 (0.41) ERN1ESR1ESR2TRIM24TRIM33
Hydrochloric Acid SCHEMBL11130190 0.79 ESR1 (0.44) CYP1A2ESR1ESR2HSD17B1HSD17B2
SCHEMBL11903615 0.78 ERN1 (0.50) ERN1ESR1ESR2TRIM24TRIM33
SCHEMBL29953364 0.78 NQO2 (0.55) ERN1CYP1A2ESR1ESR2TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106631980-B A kind of water-soluble biological thiol two-photon fluorescence probe and its preparation method and application 济南大学 2019-01-25 CN claimed
US-7265146-B2 Integrin receptor inhibitors GENENTECH, INC. (US) 2007-09-04 US claimed
US-20050187284-A1 Integrin receptor inhibitors GENENTECH, INC. (US) 2005-08-25 US claimed
EP-1330430-A2 INTEGRIN RECEPTOR INHIBITORS GENENTECH, INC. (US) 2003-07-30 EP claimed
US-20020035104-A1 Integrin receptor inhibitors GENENTECH, INC. 2002-03-21 US claimed
WO-2002016313-A2 INTEGRIN RECEPTOR INHIBITORS GENENTECH, INC. (US) 2002-02-28 WO claimed
WO-1993004127-A1 PROCESS FOR FORMING IMPROVED LIQUID CRYSTALLINE POLYMER BLENDS HOECHST CELANESE CORPORATION (US) 1993-03-04 WO claimed
EP-0375036-A1 Thermotropic liquid-crystalline aromatic copolymers ENICHEM S.p.A. (IT) 1990-06-27 EP claimed
EP-4745634-A1 COMPOSITION, OPTICALLY ANISOTROPIC FILM, AND COMPOUND FUJIFILM Corporation (JP) 2026-05-20 EP disclosed
US-20260092215-A1 COMPOSITION, OPTICALLY ANISOTROPIC FILM, AND COMPOUND FUJIFILM CORPORATION (JP) 2026-04-02 US disclosed
WO-2025013902-A1 COMPOSITION, OPTICALLY ANISOTROPIC FILM, AND COMPOUND 富士フイルム株式会社 2025-01-16 WO disclosed
CN-109415304-B Method for producing iron complex and method for producing ester compound using iron complex 株式会社可乐丽 2022-07-22 CN disclosed
CN-111072650-B Benzothiazole hydrogen sulfide fluorescent probe 北京工商大学 2021-04-06 CN disclosed
CN-110551065-B Deuterated Lucistanib compound and application thereof 海创药业股份有限公司 2021-02-26 CN disclosed
EP-0375036-A1 Thermotropic liquid-crystalline aromatic copolymers ENICHEM S.p.A. (IT) 1990-06-27 EP disclosed
EP-0166830-B1 NON-WOVEN ARTICLES COMPRISED OF THERMOTROPIC LIQUID CRYSTAL POLYMER FIBERS AND METHOD OF PRODUCTION THEREOF CELANESE CORPORATION (US) 1989-10-04 EP disclosed
US-4864021-A ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-09-05 US disclosed
EP-0323441-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0180897-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-14 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035104-A1 Integrin receptor inhibitors ITGB1, ITGA1, ITGA4 ERN1 3237/4885CYP1A2 3743/4885ESR1 1516/4885
US-20050187284-A1 Integrin receptor inhibitors ITGA4, ITGB4, ITGB1 ERN1 4129/4885CYP1A2 3720/4885ESR1 1137/4885
US-20260092215-A1 COMPOSITION, OPTICALLY ANISOTROPIC FILM, AND COMPOUND SMC1A, SMC2, SMC3 ERN1 2602/4885CYP1A2 2993/4885ESR1 1651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.