Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954832 | 0.87 | TDP1 (0.58) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL276717 | 0.83 | HTT (0.60) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL31139772 | 0.83 | HTT (0.60) | HTTTDP1LMNASMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL8501645 | 0.82 | HTT (0.58) | HTTTDP1LMNASMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL10955241 | 0.81 | HTT (0.57) | HTTTDP1LMNASMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL11387243 | 0.81 | HTT (0.57) | HTTTDP1LMNASMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL10949926 | 0.80 | HTT (0.55) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL8977874 | 0.79 | HTT (0.68) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL4606843 | 0.78 | HTT (0.54) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL10836987 | 0.78 | HTT (0.54) | HTTTDP1LMNASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |