Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953366 | 0.87 | HTT (0.60) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL9082918 | 0.83 | TDP1 (0.58) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL11570652 | 0.81 | TDP1 (0.55) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL11570647 | 0.81 | TDP1 (0.55) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL11430658 | 0.78 | TDP1 (0.53) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL29441283 | 0.78 | HTT (0.72) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL527567 | 0.78 | HTT (0.72) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL29954598 | 0.77 | ALDH1A1 (0.60) | TDP1HTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10966874 | 0.77 | ALDH1A1 (0.60) | TDP1HTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29954789 | 0.76 | ALDH1A1 (0.49) | TDP1HTTLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |