Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952250 | 0.86 | POLB (0.40) | POLBRORCCSNK2A1PARP10MAP4K4 | |
| SCHEMBL29955920 | 0.79 | CSNK2A1 (0.54) | POLBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29953167 | 0.78 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DPARP10 | |
| SCHEMBL29955933 | 0.76 | PARP10 (0.40) | POLBPARP10MAP4K4ALDH1A1 | |
| SCHEMBL29951339 | 0.76 | RORC (0.43) | POLBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29951310 | 0.76 | PDE4A (0.50) | POLBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL18003630 | 0.75 | POLB (0.49) | POLBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL14784352 | 0.75 | ERN1 (0.44) | POLBPDE4BCSNK2A1TDP1 | |
| SCHEMBL5883440 | 0.74 | ALDH1A1 (0.55) | KDM4EALDH1A1TSHRTDP1MAPT | |
| SCHEMBL21643943 | 0.74 | ALDH1A1 (0.53) | POLBALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |