SCHEMBL29953413

SCHEMBL29953413

CCNC(=O)CCOc1cccc(C=O)c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
MAOA P21397 5/20 0.47
MAOB P27338 5/20 0.47
HPGD P15428 1/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 1/20 0.46
RECQL P46063 1/20 0.46
OPRM1 P35372 1/20 0.44
OPRD1 P41143 1/20 0.44
KDM4E B2RXH2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2556831 0.86 MAOA (0.49) ALDH1A1MAOAMAOBRAB9ANPC1
SCHEMBL29952545 0.86 ALDH1A1 (0.60) ALDH1A1MAOAMAOBHPGDRAB9A
SCHEMBL29957961 0.83 ALDH1A1 (0.53) ALDH1A1HPGDRAB9ANPC1TSHR
SCHEMBL2560878 0.83 SMN1; SMN2 (0.61) MAOAMAOBHPGDRAB9ANPC1
SCHEMBL11783243 0.82 NPC1 (0.52) ALDH1A1MAOAMAOBRAB9ANPC1
SCHEMBL9458509 0.82 RECQL (0.47) ALDH1A1MAOAMAOBRAB9ANPC1
SCHEMBL21597985 0.80 CNR2 (0.52) HPGDSMN1; SMN2
SCHEMBL30688499 0.80 MAOA (0.58) ALDH1A1MAOAMAOBRAB9ANPC1
SCHEMBL2554151 0.80 MAOA (0.58) ALDH1A1MAOAMAOBRAB9ANPC1
SCHEMBL29953444 0.79 CNR2 (0.59) MAOAMAOBHPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed