Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952583 | 0.90 | RAB9A (0.52) | RAB9ANPC1MGLLMAOBPOLB | |
| SCHEMBL23452687 | 0.90 | RAB9A (0.52) | RAB9ANPC1MGLLMAOBPOLB | |
| SCHEMBL15330140 | 0.86 | NPC1 (0.53) | RAB9ANPC1MGLLMAOBPOLB | |
| SCHEMBL29951111 | 0.85 | NPC1 (0.52) | RAB9ANPC1MGLLMAOBPOLB | |
| SCHEMBL29953335 | 0.83 | NPC1 (0.53) | RAB9ANPC1MGLLMAOBPOLB | |
| SCHEMBL29953911 | 0.82 | KMT2A (0.60) | RAB9ANPC1MGLLMAOBPOLB | |
| SCHEMBL29951720 | 0.82 | NPC1 (0.67) | RAB9ANPC1MGLLMAOBPOLB | |
| SCHEMBL29956922 | 0.82 | NPC1 (0.52) | RAB9ANPC1MGLLMAOBPOLB | |
| SCHEMBL8247251 | 0.82 | NPC1 (0.55) | RAB9ANPC1MGLLMAOBPOLB | |
| SCHEMBL8251885 | 0.82 | RAB9A (0.55) | RAB9ANPC1MGLLMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |