Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 9/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.48 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950949 | 0.81 | KDM1A (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL29952551 | 0.77 | HRH3 (0.45) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL29954942 | 0.77 | KDM1A (0.39) | CHRNB2CHRNA4CHRNA7ALDH1A1 | |
| SCHEMBL12165287 | 0.73 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA2 | |
| SCHEMBL29957110 | 0.71 | CYP2A6 (0.58) | CHRNB2CHRNA4CHRNA3CHRNA7 | |
| SCHEMBL25004996 | 0.70 | FFAR1 (0.55) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA2 | |
| SCHEMBL18929330 | 0.70 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA2 | |
| SCHEMBL1959773 | 0.70 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA2 | |
| SCHEMBL1959770 | 0.70 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA2 | |
| SCHEMBL23994457 | 0.70 | FFAR1 (0.55) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |