Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950949 | 0.79 | KDM1A (0.36) | KDM1ACHRNB2CHRNA4 | |
| SCHEMBL6262582 | 0.78 | KDM1A (0.43) | KDM1AMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29953508 | 0.77 | CHRNB2 (0.50) | CHRNA7ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL6267026 | 0.75 | FFAR1 (0.46) | KDM1AMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18984025 | 0.74 | CHRNA7 (0.50) | KDM1AMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18983876 | 0.74 | CHRNA7 (0.53) | KDM1AMAOAMAOBNNMTCHRNA7 | |
| SCHEMBL9738148 | 0.74 | CHRNA7 (0.44) | KDM1AMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29952551 | 0.72 | HRH3 (0.45) | KDM1AMAOAMAOBCHRNA7CHRNB2 | |
| SCHEMBL6265823 | 0.72 | KDM1A (0.41) | KDM1AMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6263545 | 0.72 | FFAR1 (0.51) | KDM1AMAOAMAOBNNMTCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |