Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955130 | 0.80 | PDGFRB (0.35) | POLBPDGFRBPDGFRAMAP4K4LNPEP | |
| SCHEMBL29954396 | 0.77 | POLB (0.36) | POLBPDGFRBPDGFRAMAP4K4LOX | |
| SCHEMBL29956159 | 0.75 | MAP4K4 (0.42) | MAP4K4LNPEP | |
| SCHEMBL29956175 | 0.73 | POLB (0.36) | POLBLOXLOXL2 | |
| SCHEMBL29951528 | 0.73 | POLB (0.39) | POLBLOXLOXL2 | |
| SCHEMBL29955813 | 0.73 | CSF1R (0.36) | POLBPDGFRBPDGFRA | |
| SCHEMBL29958036 | 0.73 | ABL1 (0.37) | PDGFRBPDGFRAMAP4K4LNPEP | |
| SCHEMBL24323923 | 0.73 | PDGFRB (0.40) | POLBPDGFRBPDGFRA | |
| SCHEMBL29600856 | 0.73 | PDGFRB (0.40) | POLBPDGFRBPDGFRA | |
| SCHEMBL29955108 | 0.73 | PARP10 (0.37) | POLBMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |