Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | CHUK | O15111 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953815 | 0.80 | POLB (0.39) | POLB | |
| SCHEMBL29953293 | 0.75 | MAP4K4 (0.42) | POLBIRAK4 | |
| SCHEMBL29958512 | 0.75 | HCAR3 (0.40) | POLBSCD | |
| SCHEMBL29956175 | 0.73 | POLB (0.36) | POLBCSNK2A1LOXLOXL2 | |
| SCHEMBL29953531 | 0.73 | POLB (0.34) | POLBLOXLOXL2 | |
| SCHEMBL29955617 | 0.73 | POLB (0.39) | POLBSCD | |
| SCHEMBL29951171 | 0.73 | CSNK2A1 (0.50) | POLBCSNK2A1LOXLOXL2IKBKB | |
| SCHEMBL30531824 | 0.72 | POLB (0.49) | POLB | |
| SCHEMBL29957202 | 0.72 | POLB (0.37) | POLBCSNK2A1LOXLOXL2 | |
| SCHEMBL29955920 | 0.70 | CSNK2A1 (0.54) | POLBCSNK2A1LOXLOXL2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |