Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953724 | 0.80 | KMT2A (0.38) | KMT2AMAP3K7TAB1 | |
| SCHEMBL26097180 | 0.77 | CYP2A6 (0.41) | KMT2APIM3 | |
| SCHEMBL29951288 | 0.76 | KMT2A (0.47) | KMT2ACAMKK2MAP3K7TAB1KDM4E | |
| SCHEMBL29956991 | 0.75 | KMT2A (0.36) | KMT2AMAP3K7TAB1KDM4EALDH1A1 | |
| SCHEMBL9923093 | 0.73 | CAMKK2 (0.38) | CAMKK2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13040462 | 0.71 | KMT2A (0.38) | KMT2AALDH1A1 | |
| SCHEMBL12655167 | 0.68 | KMT2A (0.41) | KMT2AMAP3K7TAB1 | |
| SCHEMBL24765630 | 0.68 | LRRK2 (0.47) | JAK3 | |
| SCHEMBL29952807 | 0.68 | CYP2A6 (0.38) | KMT2AKDM4E | |
| SCHEMBL17843962 | 0.67 | KMT2A (0.51) | KMT2AALDH1A1CLK4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |