Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 2/20 | 0.32 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957323 | 0.79 | CA1 (0.36) | CA1CA2MEN1LMNATHRB | |
| SCHEMBL29952660 | 0.78 | PARP10 (0.40) | CA1CA2 | |
| SCHEMBL2818914 | 0.77 | SRC (0.55) | CA1CA2LMNASRCERN1 | |
| SCHEMBL29952700 | 0.76 | MCHR1 (0.39) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL6013337 | 0.76 | CA1 (0.44) | CA1CA2MEN1LMNATHRB | |
| SCHEMBL29954655 | 0.76 | CA1 (0.39) | CA1CA2MEN1LMNATHRB | |
| SCHEMBL29956893 | 0.76 | CA1 (0.39) | CA1CA2TDP1SRCERN1 | |
| SCHEMBL29958451 | 0.75 | MAP4K4 (0.32) | POLB | |
| SCHEMBL3579232 | 0.74 | POLB (0.49) | CA1CA2MEN1LMNAKMT2A | |
| SCHEMBL9212970 | 0.74 | CA1 (0.61) | CA1CA2MEN1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |